National NWO-CW/UU Single Crystal Service Facility

Bijvoet Centre for Biomolecular Research

Utrecht University

Padualaan 8, 3584 CH Utrecht, The Netherlands

Please Contact:
Prof. Dr. A.L. Spek
Telephone 030-2532538
Fax 030 -2533940
E-mail (A.L.SPEK@CHEM.UU.NL)

PRICE LIST (as of July 2000)

1. STANDARD PACKAGE (2500 EURO)

   1. This package includes the structure determination of a molecule with up to 50 non-hydrogen atoms. Crystals should be non-twinned, not smaller than 0.01 mm^3 and not too air-sensitive. The structure determination includes standard data collection, data reduction (including empirical correction for absorption where appropriate) and refinement (including hydrogen atoms at calculated positions) procedures. The absolute configuration is determined when relevant. Results will be reported in the form of an extensive (PLATON/CALC) listing (experimental details, coordinates, bond-distances, bond angles, torsion angles etc.) in A4 format and one or more labelled PLATON/ORTEP and PLATON/PLUTON illustrations of the structure.

   2. Additional non-hydrogen atoms - per atom 50 EURO
      (Price includes anisotropic refinement with attached hydrogen atoms at calculated positions).

2. ADDITIONAL FEE FOR NON-STANDARD OPTIONS

   1. Structure determination on a twinned crystal - 500 Euro.

   2. Refinement with a (severe) disorder model - 500 Euro

   3. Refinement procedure to improve the accuracy of a structure containing highly disordered solvents (with the SQUEEZE algorithm) - 500 Euro.

   4. Three Day Result Service (Standard Structures Only) - 1250 Euro

   5. Primary and Derived data on CD-Rom - 125 Euro

   6. Write-up of the experimental, supplementary material and drawings suitable for publication - 250 Euro
      (Free-of-Charge when supplied as co-author)

   7. A licence to use a copy of the detailed structure analyses program PLATON locally - 5000 Euro
      This licence (including later releases) is free of charge together with five standard structure determinations (or equivalent amount).

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   GENERAL RULES

   • There will be no charge for structure determinations for which no satisfactory (i.e. crystallographic R-factor higher than 10%) results (i.e. final report) can be obtained, due to poor crystal quality (i.e. the structure determination will be aborted at an early stage, unless agreed upon otherwise).

   • The minimum charge is 2500 Euro (ex VAT). This also applies when reliable results different from those expected are obtained. (Byproduct, starting material etc.)

   • The number of atoms to be charged is based on the number of non-hydrogen atoms for which positions are determined and refined (unless agreed upon otherwise).
     Note: Some crystal structures contain more than one independent copy of the same molecule along with solvent molecules of crystallization.

   • Charges for additional options will be effective only on explicit request for that option by the client.

   • Preliminary results (i.e. not necessarily refined and checked for all details) will in general be available within two weeks, after the receipt and acceptance of a sample of crystals with sufficient quality, for a standard structure determination (unless agreed upon otherwise).

   • All data and results will be treated confidentially and not made known/available to third parties unless agreed upon otherwise.

   • The client has the obligation to inform us about special precausions required for the storage, handling and disposal of the sample supplied.

   • The client is free to publish the results of the structure determination. However, we can accept 'scientific responsibility' for published crystallographic results only as a co-author of the publication and after verification of the relevant experimental and discussion sections of the paper.

   DISCLAIMER (IN DUTCH)

   "De afnemer (= opdrachtgever) vrijwaart de uitvoerder voor alle aanspraken naar aanleiding van schade, welke voortvloeit uit de commerciele exploitatie of ander gebruik van de resultaten van het onderzoek. Voorts mag het laboratorium, volgens universitaire regelingen, geen enkele garantie geven met betrekking tot de juistheid of de bruikbaarheid van de resultaten"

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   National NWO-CW/UU Single Crystal Service Facility